What should the partial pressure of oxygen (PaO2) be maintained at in the ARDS protocol?

In the context of managing Acute Respiratory Distress Syndrome (ARDS), maintaining an appropriate partial pressure of oxygen (PaO2) is crucial for ensuring that patients receive adequate oxygenation while minimizing the risk of lung injury due to excessive oxygen levels. The recommended target for PaO2 in ARDS protocols is between 55-80 mm Hg. This range strikes a balance, allowing for sufficient oxygen delivery to tissues while reducing the risk of oxygen toxicity and related complications.

Targeting a PaO2 of 55-80 mm Hg aligns with protective lung ventilation strategies commonly employed in the management of ARDS, which emphasize lower tidal volumes and controlled ventilation. By doing so, healthcare providers can effectively optimize oxygenation without compromising lung function or exacerbating the patient's condition. Therefore, maintaining PaO2 within this specified range is essential in ARDS treatment protocols.