What is the ideal tidal volume (VT) range according to the ARDS net protocol?

The ideal tidal volume (VT) range according to the ARDSnet protocol is specifically 4-6 ml/kg of predicted body weight. This recommendation is based on the findings from clinical studies that show using lower tidal volumes can help minimize ventilator-induced lung injury and improve outcomes in patients with Acute Respiratory Distress Syndrome (ARDS). Administering tidal volumes in this range helps to reduce overdistension of alveoli, improve oxygenation, and promote better gas exchange while reducing the risk of further lung injury.

Using higher tidal volumes, as seen in the other ranges provided, can lead to barotrauma and volutrauma, which are particularly detrimental in patients with compromised lung function, such as those with ARDS. Therefore, the evidence-based guidelines strongly support the use of 4-6 ml/kg as the safest and most effective approach to mechanical ventilation in these patients.